Revista Mexicana de Oftalmología

Register      Login

VOLUME 97 , ISSUE 5E ( September-October, 2023 ) > List of Articles


Meningoencephalitis associated with Third Cranial Nerve Palsy by SARS-CoV-2: Report of a Case

Ana L Tapia-Álvarez, Othón Gittins-Núñez, Alejandro Flores-Trejo, Patricia A Dominguez-Álvarez

Keywords : Infection, Meningoencephalitis, Neuritis, Paralysis, RT-PCR, SARS-CoV-2

Citation Information : Tapia-Álvarez AL, Gittins-Núñez O, Flores-Trejo A, Dominguez-Álvarez PA. Meningoencephalitis associated with Third Cranial Nerve Palsy by SARS-CoV-2: Report of a Case. 2023; 97 (5E):130-133.

DOI: 10.5005/rmo-11013-0063

License: CC BY-NC-ND 4.0

Published Online: 27-03-2024

Copyright Statement:  Copyright © 2023; Sociedad Mexicana de Oftalmología.


Objective: To inform the ophthalmologist of the importance of ruling out the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in the current context of this pandemic, in a patient with neuro-ophthalmological symptoms without respiratory compromise. Observation: 41-year-old male presented to the ophthalmologist for palsy of the III and IV cranial nerves and anterior optic neuritis of the left eye. A Polymerase Chain Reaction (PCR) test was requested for SARS-CoV-2 being positive. Conclusions: Neuro-ophthalmological involvement in a patient with SARS-CoV-2 infection is an alarm data for a severe course of the disease, diagnosing it in the absence of respiratory symptoms is a diagnostic challenge, we must carry out a careful questioning about a recent history of respiratory symptoms or fever, and perform RT-PCR for SARS-CoV-2, avoid delays in its diagnosis, will improve the prognosis of life of the patient.

PDF Share
  1. Moriguchi T, Harii N, Goto J, Harada D, Sugawara H, Takamino J, et al. A first case of meningitis/encephalitis associated with SARS-Coronavirus-2. International Journal of Infectious Diseases 2020 Abril; 94(55-58).
  2. Orozco-Hernández JP, Marin-Medina DS, Sánchez-Duque JA. Manifestaciones neurológicas de la infección por SARS-CoV-2. Semergen 2020 Agosto; 46(112-116).
  3. Wu Y, Xu X, Chen Z, Duan J, Hashimoto K, Yang L, et al. Nervous system involvement after infection with COVID-19 and other coronaviruses. Brain, Behavior, and Immunity 2020 julio; 87(18-22).
  4. Dinkin M, Gao V, Kahan J, Bobker S, Simonetto M, Wechsler P, et al. COVID-19 presenting with ophthalmoparesis from cranial nerve palsy. Neurology. 2020 Mayo; 95(221-223).
  5. Mao, Jin, Wang M, Hu Y, Chen, He Q, et al. Neurologic Manifestations of Hospitalized Patients With Coronavirus Disease 2019 in Wuhan, China. JAMA Neurology 2020 Abril; 77(6).
  6. Pascual-Prieto J, Narváez-Palazón C, Porta-Etessam J, Gómez-de-Lian R. Epidemia COVID-19: ¿debe el oftalmólogo estar alerta ante las paresias oculomotoras. ARCHIVOS DE LA SOCIEDAD ESPAÑOLA DE OFTALMOLOGÍA 2020 Julio; 95(7).
  7. Gutiérrez-Ortiz C, Méndez-Guerrero A, Rodrigo-Rey, San Pedro-Murillo, Bermejo-Guerrero, Gordo-Mañas, et al. Miller Fisher syndrome and polyneuritis cranialis in COVID-19. Neurology 2020 Agosto; 95(5).
  8. Pérez-Bartolomé F, Sánchez-Quirós J. Manifestaciones oftalmológicas del SARS-CoV-2: Revisión de la literatura. ARCHIVOS DE LA SOCIEDAD ESPAÑOLA DE OFTALMOLOGÍA 2020 Agosto.
  9. A.A. Douglas K, Paraskevi D. V, Moschos MM. Ocular Manifestations of COVID-19(SARS-CoV-2): A Critical Review of Current Literature. International Journal of Experimental and Clinical Pathophysiology and Drug Research 2020 Junio; 34(3).
  10. Ahmad I, Azam Rathore F. Neurological manifestations and complications of COVID-19: A literature review. Journal of Clinical Neuroscience 2020 Mayo; 77(8-12).
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.